May 22 Mutated COVID-19 may predict a great risk for humanity in the future
Dawood AA
ABSTRACT
Coronavirus disease 2019 SARS-CoV-2 (COVID-19) is a zoonotic virus that causes a variety of severe respiratory illnesses.
SARS-CoV-2 is closer to SARS-CoV and MERS-CoV in structure.
The high prevalence of COVID-19 is a result of the lack of symptoms at onset. Our aim of the study was to present an overview of the virus in terms of structure, epidemiology, symptoms, treatment and prevention.
The sequences of the genome and some viral proteins were investigated to determine gaps and changes in the alternation of nucleotides and amino acids.
11 complete genome sequences of different coronaviruses were sequenced and evaluated using BAST and MAFFT software. Seven types of structural proteins were also selected. It was concluded that COVID-19 could produce new mutations, specifically in glycoproteins, so caution and full preparation by health authorities will be necessary.