Laboratory abnormalities in patients with COVID-2019 infection

Hussin A. Rothana, Siddappa N. Byrareddy

Laboratory abnormalities in patients with COVID-2019 infection

Giuseppe Lippi and Mario Plebani

Clin Chem Lab Med. 2020 Mar 3. pii: /j/cclm.ahead-of-print/cclm-2020-0198/cclm-2020-0198.xml. doi: 10.1515/cclm-2020-0198. [Epub ahead of print]

ABSTRACT

Although the clinical features of COVID-19 have been broadly defined, a summary of the most representative laboratory abnormalities found in patients with COVID-2019 infection is lacking. It has already been highlighted previously that the laboratory plays an essential role for medicine in the early detection, diagnosis and management of many diseases. COVID-19 is no exception to this rule, whereby real-time reverse transcription polymerase chain reaction (rRT-PCR) allows direct identification of viruses, while detection of anti-COVID-19 antibodies. XNUMX of the immunoassays are the mainstay of serological surveillance.

However, the role of laboratory diagnosis extends far beyond etiological and epidemiological diagnosis for surveillance, so in vitro diagnostic tests are commonly used to assess disease severity and define prognosis, for follow-up. of patients, to guide treatment and for their therapeutic follow-up. Therefore, the objective of this article is to provide a brief description of the most frequent laboratory abnormalities found in patients with COVID-2019 infection.